Pripyat City Hall housed a number of local and regional government organizations. It was the main administrative institution of Pripyat. After the Chernobyl disaster the offices was home to several enterprises that dealt with the aftermath of the disaster.

Firstly the City Hall housed the city executive committee. The head of the Executive Committee, the Soviet equivalent of the mayor, was Vladimir Voloshko. But more important, there was also office for the city committee of the CPSU, the Communist Party of the Soviet Union. Due to the one-party system, the status of a CPSU member was more important than the status of the city council. Also the Komsomol city committee, or the Leninist Ukrainian Communist Youth League, had office here. On the top floor of the City Hall there was a department of the KGB.

After the Chernobyl disaster the offices were not abandoned. It was used by State Enterprise Kompleks, or in Russian «Комлпекс». It was a specialized enterprise for radioactive waste management and decontamination. Before the accident, Kompleks was an ordinary concrete plant. But after April 1986 it purpose was to clean the Chernobyl Exclusion Zone from radioactive substances. The company also owns the parking of robots and robotic equipment that worked to eliminate the accident. They are so radioactive that decontamination is not possible.

Other organizations working in the old City Hall were ПО «Комбинат» and the scientific research-to-production facility НПО «Припять». They were meant to bridge the gap between design and production, to speed up results. The building is abandoned since 2001.